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China Thiophene C4H4S Suppliers - High-Quality Factory Product CAS: 110-02-1 for Chemical Applications
Thiophene is a five-membered heterocyclic compound containing one sulfur atom. It exists in small amounts in crude benzene obtained from coal tar and is a colorless liquid with a similar aromatic odor to benzene.
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Physical Properties
Boiling point is 84℃. It is insoluble in water but soluble in ethanol, ether, acetone, benzene, carbon tetrachloride, heptane, pyridine, and 1,4-dioxane.
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Stability & Resistance
Strong heat resistance (no decomposition at 850℃). It does not polymerize or oxidize under strong acid conditions.
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Chemical Structure
Five atoms on the thiophene ring are sp2 hybridized in a single plane, forming a closed conjugated system with six electrons, providing aromaticity.
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Reactivity
More prone to electrophilic substitution than benzene, primarily at the α-position (2 or 5). It can undergo sulfonation at room temperature.
The important derivative of thiophene is biotin. Thiophene is flammable and has moderate toxicity. Because it produces 2-thiophene sulfonic acid when reacted with concentrated sulfuric acid (which is soluble in the acid), this method is standard for removing thiophene from crude benzene.
Frequently Asked Questions
Q1: What are the primary physical characteristics of Thiophene?
Thiophene is a colorless liquid with an aromatic odor similar to benzene, a boiling point of 84℃, and it is flammable with moderate toxicity.
Q2: Is Thiophene soluble in water?
No, Thiophene is insoluble in water. However, it is highly soluble in organic solvents like ethanol, ether, benzene, and acetone.
Q3: How does Thiophene demonstrate aromaticity?
The five atoms in the ring are sp2 hybridized and coplanar. The sulfur atom's unshared electron pair overlaps with the p orbitals of the four carbon atoms to form a conjugated system of six electrons.
Q4: What is the thermal stability of Thiophene?
Thiophene exhibits exceptional heat resistance and does not decompose even when heated to temperatures as high as 850℃.
Q5: How is Thiophene typically removed from crude benzene?
It is removed through a sulfonation reaction with concentrated sulfuric acid at room temperature, which produces soluble 2-thiophene sulfonic acid.
Q6: What is a well-known biological derivative of Thiophene?
Biotin (Vitamin B7) is one of the most important biological derivatives of the thiophene structure.