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Sulfamide H4N2O2S CAS:7803-58-9 - Premium Quality from China Suppliers and Factory
White or off-white crystalline substances. They are soluble in alcohols and hot water but insoluble in cold water, ether and benzene. At room temperature, they can absorb dry ammonia gas to form colorless ammonia complexes. They are stable in acidic, neutral and alkaline aqueous solutions.
- 🛡️ Stability: Excellent stability in acidic, neutral, and alkaline aqueous solutions.
- ⚗️ Versatility: Compatible with transition metal-catalyzed cross-linking and nucleophilic alkylation.
- 🧪 Reagent Source: Recognized as the optimal reagent source for sulfonamide groups in late-stage synthesis.
Sulfonamide has the properties of stability, availability and compatibility in various reaction conditions, including transition metal-catalyzed cross-linking reactions, amide/ester formation reactions, nucleophilic alkylation reactions, etc. Therefore, sulfonamide compounds are the best reagent sources for sulfonamide groups in the later stage.
Frequently Asked Questions
What is the physical appearance of Sulfonamide?
Sulfonamide typically appears as white or off-white crystalline substances.
What are the solubility properties of these compounds?
They are soluble in alcohols and hot water, but remain insoluble in cold water, ether, and benzene.
How does Sulfonamide behave in different pH levels?
Sulfonamide is highly stable in acidic, neutral, and alkaline aqueous solutions, making it versatile for various chemical environments.
What happens when it reacts with dry ammonia gas?
At room temperature, Sulfonamide can absorb dry ammonia gas to form colorless ammonia complexes.
What chemical reactions is Sulfonamide compatible with?
It is compatible with transition metal-catalyzed cross-linking, amide/ester formation, and nucleophilic alkylation reactions.
Why is it considered a preferred reagent in late-stage synthesis?
Due to its stability and compatibility, it is the best reagent source for introducing sulfonamide groups during the later stages of chemical reactions.

